Is There Room for LMWH Treatment in Obstetrics Gynecology?

摘要

Low molecular weight heparins (LMWHs) are substituting unfractionated heparins for various indications for anticoagulant therapy in perinatal medicine. Compared with unfractionated heparin, LMWHs have longer bio avail ability and lower frequency of serious side effects, and have a more predictable dose-response without laboratory monitoring. LMWHs are more convenient to the patients and safe for the fetus. In addition to the treatment and prevention of venous thromboembolic (VTE) events throughout gestation and puerperium, LMWHs are currently prescribed for the prevention of recurrent pregnancy complications. Planned induction of labor or elective abdominal birth is desirable in order to decrease bleeding and regional analgesia-related complications.