We address some of the current challenges in intelligent interfaces for universal access and present the design of an intelligent interface which is aimed at 1) input processing the user's sensory modalities (or modes) via various media, 2) building (or encoding) a model of the user's emotions (MOUE) and 3) adapting its multimedia output to provide the user with an easier and more natural technology access and interaction. We identify key research issues relating to one particularly rich application of MOUE, namely home health care provided via telemedicine.
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