The Study of Outgrowth and Differentiation Effects of bFGF and EGF on Neural Stem Cells in Primary Culture

摘要

bFGF and EGF both can enhance the outgrowth and differentiation of neural stem cells in primary culture; EGF may promote the proliferation of neural stem cell and exerts a preferential effect on glial development; FGF mainly affects neuronal development and, to a lesser extent, glial development. The combination of these two factors both can increase NSE and GFAP reactivity.