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Alginate micro-bead fabrication on a centrifugal microfluidics platform

机译:离心微流体平台的海藻酸盐微珠制造

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We present a novel method for the direct, centrifugally induced fabrication of small alginate beads displaying adjustable diameters between 180 μm and 800 μm by polymer-tube micronozzles. The size distribution features a CV of 7 – 16 % for the main peak. Up to 600 beads per second and channel are issued from the micronozzle through an air gap towards a standard lab tube (“Eppi”) attached to the rotor spinning and containing a curing agent. At spinning frequencies between 5 Hz and 28 Hz, the tubes align horizontally under rotation and return to a vertical position as soon as the rotor is at rest. The hardened beads are collected within the tube for further processing or characterization. This method is considered as a low cost technology for micro encapsulation technologies.
机译:我们提出了一种新的用于直接,离心诱导的小海藻珠粒制备的方法,所述小海藻珠粒通过聚合物 - 管微漆显示在180μm和800μm之间的可调直径。尺寸分布为主峰的CV为7-16%。每秒高达600个珠子和通道通过朝向标准实验室管(“EPPI”)附着在转子旋转并含有固化剂的标准实验室管(“EPPI”)上发出。在5Hz和28Hz之间的旋转频率,管道在旋转下水平对齐,一旦转子静止,就会返回到垂直位置。将硬化的珠子收集在管内以进一步加工或表征。该方法被认为是微包装技术的低成本技术。

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