Modelling and Supervision of Intra-Pertioneal Chemohyperthermia (IPCH)

摘要

Intraperitoneal chemohyperthermia is more and more considered as an interesting therapeutic option in cases of some abdominal cancers, particularly of digestive origin. However, many technical aspects of this treatment remain far from being mastered, particularly the homogeneous dispatch of temperatures and drugs within the abdomen cavity. The project described in this paper consists, first of all: in an experimetnal study, which has been carried out on a physical, in vitro prototype of the abdomen, on which different hot fludi flows and injection conditions (configurations) are investigated. The results of this experimental study have enabled to obtain a model of the system behaviour. The modelling results have helped to optimize the injection circuit and its running parameters while applied to the in vivo treatment of patients. Copyright direct C 2000 IFAC