Surface treatment of glassy polymeric carbon artifacts for medical applications

摘要

Glassy Polymeric Carbon (GPC) has been used for mechanical caridac valves. GCP valves are chemically biocompatible and durable, but less thromboresistant than biological valves. Enhanced thromboresistance of mechanical cardiac components with porous surface has been demonstrated. The endothelialized tissue blood-contacting surface adheres to the proos prosthetic component and decreases the formation of thrombus. Our experience has shown that the porosity of GPC can be increased and controlled by MeV ion bombardment. We report here that the surface roughness of heat-treated GPC bombarded with C, O, Si and Au is also enhanced. The surface prougness of the ion-bombarded samples is on a smaller scale than those roughnended by sand blasting (measurements made with Perthomete S8P). The roughness decreaes slighly after heat treatment, in linear proportion to the shrinkage of the test piece. Possible beneficial effects of the imbedded ions on tissue adherence and htromboresistance must be determined by in vivo animal experiments.