Co_3-apatite preparations with solubility gradient: potential degradable biomaterials

摘要

The purpose of this study was to prepare and characterize CO_3 apatite material, which will have a degradable outer layer and a relatively stable core to provide potential biomaterials with solubility gradient. The materials were synthesized at 80 +- 1deg C and pH 7.4 +- 0.2, by simultaneously feeding Solution I and Solution II into mechanically stirred 1.3 mol/L acetate buffer solution. Solution I consisted I of 0.5 L of 100 mmol/L Ca(CH_3COO)_2; Solution II consisted of 0.5 L of 60 mmol/L NH_4H_2PO_4 solution into which a constant concentration of 95 mmol/L (NH_4)_2CO_3 was fed. The preparations were characterized using x-ray diffraction (XRD), scanning electron microscopy (SEM) and electron spectroscopy.