Background: Air pollution and pregnancy outcomes have been widely described, however less is known about the temporal fluctuations and their health impact. Southwest communities in Bogota are the most vulnerable population to air pollution having a PM10 annual average of nearly 80 mcg/m3. Aim of the study was to identify potential adverse effects during advanced pregnancy according to the temporal patterns of air pollution in a deprived community in Bogota. Methods: A cross sectional study of women from 28 to 42 weeks of pregnancy that assisted at a second level hospital in Bogota's Southwest during 2016 was carried out. The sample included 126 women that were divided in two groups: A group of high levels of exposure that had their pregnancy during the dry season and the other one that had their pregnancy during the rainy season. PM10 was used as exposure variable and the outcomes were birth weight, systolic and diastolic blood pressure. PM10 level was adjusted by rainfall and temperature. Statistical analysis included t-test for independent samples and linear regression. Results: There were differences between mean PM10 during dry season (89 mcg/m3) and mean PM10 during the rainy season (66 mcg/m3) (p<0,05). Birth weight was significantly less (Mean difference=-388,1 gr, Ul 95%: -507 a -268) in the group of high levels of exposure (2903kg ± 358,4) compared to the other group (3291kg±288,l). Such difference persisted during lineal regression after adjusting for temperature and cumulative rainfall (Beta=0.59 p<0.05). Other outcomes that were assessed did not show significant differences according to the levels of exposure. Conclusions: A temporal pattern of air pollution exposure and birth weight was observed in a polluted area of Bogota. Such findings have implications in maternal and child health and outline the importance of including these temporal variations on air pollution surveillance and control initiatives.
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机译：背景：空气污染和妊娠结局已得到广泛描述，但对时间波动及其对健康的影响知之甚少。波哥大的西南社区是最容易受到空气污染的人口，其PM10年平均水平接近80 mcg / m3。该研究的目的是根据波哥大一个贫困社区的空气污染的时间模式，确定晚期妊娠期间的潜在不良反应。方法：2016年在波哥大西南部的一家二级医院进行了一项针对怀孕28至42周的妇女的横断面研究。样本包括126名妇女，分为两组：一组是高暴露水平，她们在旱季怀孕，而另一组则在雨季怀孕。将PM10用作暴露变量，其结果为出生体重，收缩压和舒张压。 PM10水平是通过降雨和温度调节的。统计分析包括独立样本的t检验和线性回归。结果：干燥季节的平均PM10（89 mcg / m3）和雨季的平均PM10（66 mcg / m3）之间存在差异（p <0.05）。高暴露水平（2903kg±358,4）组的出生体重明显低于其他组（3291kg±288，平均差异= -388,1 gr，Ul 95％：-507 a -268）。 l）。在调整温度和累积降雨后，线性回归期间这种差异仍然存在（Beta = 0.59 p <0.05）。根据暴露水平，评估的其他结果未显示出显着差异。结论：在波哥大的污染区域观察到空气污染暴露和出生体重的时间规律。这些发现对母婴健康产生了影响，并概述了将这些时间变化纳入空气污染监测和控制计划的重要性。
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