Phase synchronization of human cardiovascular oscillations using photoplethysmography and laser Doppler flowmetry data

摘要

Phase synchronization between breath rate, heart rate variability, blood flow and blood volume oscillations were studiedfrom healthy volunteers at rest. The degree of synchronization between the phases of the analyzed signals was estimatedfrom the value of the wavelet phase coherence. High phase synchronization between blood perfusion and blood volumeoscillations in a wide frequency range from 0.0095 to 0.1 Hz and at the frequency of heart rate (～ 1 Hz) was obtained.Significant phase synchronization were demonstrated between heart rate variability both skin blood flow oscillations andblood volume ones at the frequency of endothelial (～ 0.01 Hz) and myogenic (～0.1 Hz) activities. It was revealed highphase synchronization at the respiratory frequency (～ 0.3 Hz) for blood volume oscillations and low synchronization forblood flow ones. Also there are differences of phase synchronization of blood volume and blood flow oscillations withrespiratory rate at the breath frequency. It was obtained high phase synchronization at this frequency for blood volumeoscillations and low synchronization for oscillations of skin microvasculature. We assume that the results obtained canform the basis of new diagnostic criteria for assessing the state of the cardiovascular system in pathologies.