Multi channels Fiber Optic Reflex Probes for fluorescent and UV-VIS-NIR spectroscopy based on novel types of multimode fiber optics bundles

摘要

Multichannel Fiber Optic Probes (MFOP) is new type of accessories’ which can be used for Modern BiophotonicsTechniques, based on: UV-VIS- NIR spectroscopy, fluorescent spectroscopy. New simulations program MFOBv.3 forMFOP allow to specify basic reflex light optic value I_0 as a function of distance Z[μm] have been developed. MFOBv.3make possible quick selection and optimization of the probe fiber bundle structure and fibers specification. DesignedReflex probe for endoscopy spectral evaluations include new type of fibers. Fibers with core surrounded by hollowcircular guide provide necessary wide numerical aperture. Multimode metal coated fibers used in MFOP for tumordiagnostic in surgery. Symbioses of Microtechnology and new types of fiberoptic allow made smallest Reflex probe7+1 fibers structure (OD=0.6mm). Designed sensitive electronic system with 405nm/50mW laser synchronized withfluorescent signals measurement device. For tumor diagnostic during stomach surgery created high sensitiveendoscopic fiber multichannel probe for special photosensitizer with excitation wavelength 405 nm. Reflex probeprovide sensitivity small than 10 microgram photosensitizer for 1 kg biomass. Experimental results for bio liquids andfor tissue with laser induced fluorescence diagnostic extended in poster/report.