Biosensor platforms for biomarker detection: plasmonic aptasensors for detection of Neuropeptide Y

摘要

A Neuropeptide Y-binding aptamer (NPY-BA) and 15 nm gold nanoparticles (AuNPs) were used to createplasmonic aptasensors for the selective detection of Neuropeptide Y in a rapid colorimetric assay. In this report, wedescribe different parameters that can be varied to optimize the sensitivity and selectivity of these assay anddemonstrate initial NPY detection in sweat.