This paper presents a method of comparing protein structures basedon pairwise secondary structure topology. In this method, the spatialrelation (sometimes rough relation) between any two secondary structuralsegments in a protein is represented as an element of the matrix data.The structure comparison is achieved by comparing two matrices using apattern matching technique. In order to confirm the validity of theproposed method, experiments on similar protein retrieval was performedwhich showed that the method was effective
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