Long-term gastric pacing with a portable gastric pacemaker to aidgastric emptying in humans

摘要

Previous studies have shown that electrical stimulation of thestomach may improve gastric emptying. However, none of the previousstudies has reported the optimization of pacing parameters and thesestudies were only performed for short periods using a stationarystimulator. The aim of this study was to further investigate the effectof long-term gastric pacing with a portable stimulator on gastricemptying in patients with gastroparesis. A series of experiments withdifferent pacing parameters were conducted in 5 patients withgastroparesis to optimize the performance of the gastric pacing. Aportable gastric pacemaker was made for each patient to use at homedaily for one month. Compared with the results before pacing,significant improvement of gastric emptying was achieved after long-termpacing