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Assessing the Potential Impact of Climate Change on Mortality for the Greater Boston Area

机译:评估大波士顿地区气候变化对死亡率的潜在影响

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Rising temperatures associated with climate change are expected to impact human adaptive responses, including changes to home cooling and ventilation patterns. These changes in turn will alter the contributions of outdoor fine particulate matter (PM2.5) sources to indoor air quality, and subsequently lead to differential effects of PM2.5 exposures on human health. Therefore, the objective of this study was to examine the impact of climate change-related differences in exposures to indoor particle of outdoor origin on PM2.5-related mortality. We gathered all-cause non-accidental daily mortality data in the greater Boston area for the years 2000-2009 as the health outcome in the epidemiologic modeling. We used a negative binomial model to assess the association between the same day indoor PM2.5 concentration and total mortality, adjusted for long-term trend and ambient temperature through smoothing splines, as well as seasons using indicator variables for the past period. For the future climate change scenario, we used the health model to predict the daily total mortality under the climate of for 2056-2065. A strong, positive relationship was found between indoor PM2.5 concentration and total mortality, whereas a U-shaped relationship was seen for ambient temperature with higher mortality for colder months, followed by high temperature range. Under the future climate, there was an increase in indoor PM2.5 concentrations in warmer seasons, ranging from late spring (May) to mid-autumn (October). Overall, a similar trend was found for monthly averaged total mortality, with up to 3.6% and 3.7% increase in May and September, respectively. On the contrary, increase in temperature showed an overall protective effect (1.6 - 4.4% decrease) on mortality for colder months (January to April). Our findings suggest different adaptation strategies should be considered for colder and warmer months, respectively, to protect population health under the future climate change scenario.
机译:与气候变化相关的温度升高预计会影响人类的适应性反应,包括家庭制冷和通风方式的变化。这些变化反过来将改变室外细颗粒物(PM2.5)来源对室内空气质量的贡献,并随后导致PM2.5暴露对人体健康的不同影响。因此,本研究的目的是检验与气候变化相关的室外暴露于室内的室内颗粒暴露对PM2.5相关死亡率的影响。在流行病学模型中,我们收集了大波士顿地区2000-2009年的全因非偶然日死亡率数据。我们使用负二项式模型评估了当天室内PM2.5浓度与总死亡率之间的关联,并通过平滑样条线对长期趋势和环境温度进行了调整,并使用过去一段时间的指标变量对季节进行了调整。对于未来的气候变化情景,我们使用健康模型预测2056-2065年气候下的每日总死亡率。室内PM2.5浓度与总死亡率之间存在强烈的正相关关系,而环境温度呈U形关系,在较冷的月份死亡率较高,其次是高温范围。在未来的气候下,从春季末(五月)到中秋(十月),温暖季节的室内PM2.5浓度会增加。总体而言,月平均总死亡率也有类似趋势,5月和9月分别增加了3.6%和3.7%。相反,温度升高对寒冷月份(1月至4月)的死亡率显示出总体保护作用(降低1.6-4.4%)。我们的发现表明,在未来的较冷和较温暖的月份,应分别考虑不同的适应策略,以保护未来气候变化情景下的人口健康。

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