The new method for treatment of larynx stenosis based on transplantation of rib cartilage reshaped with 1.56 μm laser radiation

摘要

Cartilage is the best nature material for transplantation. Laser reshaping of cartilage allows obtaining anydesirable shape of the implant. This work continues the interdisciplinary studies on laser-induced development ofstable costal cartilage implants, the most promising biological object for the manufacture of implants (grafts)used in otolaryngology and maxillofacial surgery, in particular, in recovering tracheal defects for the treatment oflarynx stenosis. We used 1560 nm fiber laser with feedback control system measuring tissue temperature in thecourse of laser irradiation.The thermomechanical IR-laser effect on reshaping process for ENT is studied. The possibility and conditions ofthe laser reshaping of costal cartilage for stable human implants are investigated. The causes of nonlinearthermomechanical behavior of cartilage and its influence on controlled reshaping and stability of costal cartilagefor ENT are discussed. Clinical trials for 5 patients with one and a half year follow-up observation demonstratestable positive results.