Human breast tumor characterization on post-surgical mastectomy specimens using Harmonic Motion Imaging (HMI)

摘要

To overcome the low sensitivity of current breast imaging tools, new tools for breast imaging and evaluation must be developed for reliable identification and differentiation of breast masses based on stiffness. Recently, we have shown that Harmonic Motion Imaging (HMI) can be used to differentiate relative stiffness and monitor HIFU ablations in small lumpectomy human breast specimens. The objective of this study is to apply HMI on post-surgical mastectomy breast specimen to mimic the in vivo environment and characterize tumor at different depth for better tumor localization and identification before and after HIFU treatment.