In vivo contractile properties measurement of the biceps brachii muscle using high frame rate plane waves and k-space transverse oscillation

摘要

Amyotrophic Lateral Sclerosis (ALS) is a fatal motor neuron progressive disorder that leads to muscle deterioration and paralysis. There is a crucial need to identify new therapeutic approaches and validate methods to assess their efficacy. The objective was to develop a high frame rate vectorised approach to visualize and analyze the 2D transient contractile wave propagation of muscle tissue with the perspective to understand the link between its electrical and mechanical activities.