This paper presents a design of batteryless CMOS system-on-a-chip (SoC) with dual-mode programmable pulsed radio-frequency (PRF) stimulation, temperature detection, and wireless communication for trigeminal neuralgia alleviation on demand. The system is capable of providing square wave, sinusoid wave, and patterned stimulation waveform, and the stimulation parameters which include pulse frequency, amplitude, duty cycle, and pulse duration, can be wirelessly reconfigured by the external handheld device. The temperature sensor incorporated with analog front-end circuit can detect the temperature of body and SoC chip for the prevention of possible abnormal operation. All the information of stimulation parameters and temperature can be real-time monitored by a handheld device through wireless communication, which follows medical implanted communication system (MICS) standard. This SoC chip, whose dimension is 3.11 × 2.73 mm2, is fabricated in standard 0.35um CMOS process and mounted on a compact test board, whose size is 2.6 × 2.1 cm2, for delivering PRF stimulation in animal studies.
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机译:本文介绍了无电池CMOS系统的芯片(SOC)的设计,具有双模可编程脉冲射频(PRF)刺激,温度检测和用于三叉神经痛的无线通信。该系统能够提供方波,正弦波和图案化刺激波形,以及包括脉冲频率,幅度,占空比和脉冲持续时间的刺激参数可以通过外部手持设备无线地重新配置。加入模拟前端电路的温度传感器可以检测身体和SOC芯片的温度,以防止可能的异常操作。刺激参数和温度的所有信息都可以通过手持设备通过无线通信进行实时监控,这遵循医疗植入的通信系统(MICS)标准。这个SOC芯片,其尺寸为3.11×2.73 mm 2 sup>,由标准的0.35um CMOS工艺制造,并安装在紧凑型测试板上,其尺寸为2.6×2.1厘米 2 sup>,用于在动物研究中提供PRF刺激。
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