In 1948, Pennes [1] presented a mathematical model of heat transfer in human tissue. The effect of blood flow on heat transfer was modeled as heat sink or source whose magnitude is proportional to the volumetric perfusion rate and difference between arterial and venous temperature [2]. Pennes assumed that thermal equilibrium occurs in the capillary beds, although Chen [3] showed that it occurs in bigger vessels before the blood enters the beds. Weinbaum el al.
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机译：1948年，Pennes [1]介绍了人体组织中的热传递的数学模型。血流对热传递的影响被建模为散热器或源的幅度与动脉和静脉温度之间的体积灌注速率和差异成比例[2]。 Pennes认为热平衡发生在毛细血管床中，尽管陈[3]显示它在血液进入床之前发生在更大的血管中。 weinbaum el al。
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