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Correction of motion-induced artifacts in clinical cardiac SPECT studies using a stereo-motion-tracking system

机译:立体运动跟踪系统校正运动诱导的临床心脏SPECT研究中的伪影

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Patient body motion is inevitable in cardiac SPECT due to the lengthy interval of time patients are imaged (∼23 min with transmission scan) and even respiratory patterns can change over that period. The use of external tracking devices provides additional information which is expected to result in a more robust correction than using just the emission data. We have been investigating the use of stereo-motion-tracking of retro-reflective markers on stretchy bands wrapped about the chest and abdomen of patients to provide 6 degree-of-freedom (DOF) tracking of the patient during cardiac SPECT. Recently we have introduced a visual-tracking-system (VTS) which utilizes 5 near-infrared (NIR) cameras to track markers from both ends of the clinic. This system is robust enough to compensate for multiple cameras being blocked from viewing all the markers due to the patient anatomy or viewing geometry restrictions imposed by the SPECT system. Initial studies have shown that the temporal and spatial accuracy of this motion-tracking system are well within the precision needed to correct for motion artifacts that can occur during cardiac SPECT. Clinical trials have been initiated for list-mode cardiac SPECT studies using bands of markers on the chest and abdomen, and so far we have been able to consistently track the markers. We have begun volunteer studies with IRB approval and informed consent where patients were asked to stay for a second cardiac-rest study with no additional radioactivity. Patients were asked to perform specific movements and we were able to correct for the rigid-body motion during SPECT reconstruction with our software as well as the standard clinical tool for comparison.
机译:患者身体运动是在心脏SPECT不可避免由于时间的患者的冗长间隔进行成像(〜23分钟,透射扫描)甚至呼吸模式可以改变在此期间。使用外部跟踪装置提供被预期导致更健壮的校正比仅使用发射数据的附加信息。我们一直在研究使用的包裹患者的胸部和腹部上延展的条带的反光标志立体运动跟踪,提供学位的6自由度(DOF)心脏SPECT期间病人的跟踪。最近,我们引入了一个可视跟踪系统(VTS),其利用5的近红外(NIR)照相机来跟踪从诊所的两端标记。该系统是足够强大的,以补偿多台摄像机从观看所有标记由于患者解剖或观看由SPECT系统外加几何形状的限制被封锁。初始研究表明,该运动跟踪系统的时间和空间的精度是公需要正确对可心脏SPECT中发生的运动伪影的精度之内。临床试验已经开始使用的胸部和腹部标记带列表模式心脏SPECT研究,到目前为止,我们已经能够持续跟踪标记。我们已经开始与IRB的批准和知情同意书,其中患者被要求留下来,没有额外的放射性第二心脏休息学习志愿者研究。患者被要求执行特定的动作,我们能够纠正SPECT重建我们的软件,以及比较标准的临床工具在刚体运动。

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