Gold nanorods-based oligonucleotides carrier quantitative characterisation

摘要

Gold nanorods (GNRs) are attracting a lot of attention due to their extraordinary optical properties, and potential use for medical applications. The issue of the attachment of double stranded oligonucleotides onto GNR surfaces is crucial for the development of quantitative DNA/RNA delivery carried by GNRs. This work presents a fluorescence-based characterisation method for assessing the attachment of dsDNA to GNR surfaces.