The mechanical effects of microbubble oscillation on elastic vessel wall under ultrasonic excitation with different frequencies using finite element method

摘要

It was proposed that the bubble-vessel interaction played important role in the blood brain barrier opening associated with microbubble cavitations. The mechanical effects of microbubble oscillation on elastic vessel wall under ultrasonic excitation with different frequencies are studied by numerical simulation using fluid solid interaction. The natural frequency of microbubble oscillation is larger than that in the infinite liquid surroundings. The compressive circumferential stress with magnitude 300 kPa is not likely to induce brain microvessel endothelial lining disruption.