Research on ACE Gene I/D Polymorphism of Men and Effects of HiHiLo on SPO_2

摘要

Purposes To explore the association between Insertion/Deletion polymorphism of the angiotensin converting enzyme (ACE) gene and the effects of Living High-Exercise High-Training Low (HiHiLo) on arterial oxygen saturation (SPO_2), so that sports practitioners comprehend better individual hypoxia training effects, coach can constitute individual training program. Procedures and Methods 71 healthy men of Han nationality in northern China underwent HiHiLo training for 4 weeks Training programme was as follows: exposure in hypoxic environment (14.5-14.8 % O_2, 10 h/day), three times hypoxic training per week (15.4 % O_2), and training at sea level. Resting, exercising and resuming SPO_2 were measured before and after the protocol, and the ACE gene I/D polymorphism was detected by PCR. Results There was no significant differences were in the baseline SPO_2 among groups before HiHiLo. Exercising and resuming SPO_2 both increased significantly in total and II, ID after training than those before the training (P < 0.01), but no significant changes showed in DD (P > 0.05). Conclusions HiHiLo could be helpful for developing individual exercising and resuming SPO_2. Moreover, SPO_2 of men carrying 2 and ID probably were more sensitive to the hypoxic training than those carrying DD.