Development of an Intelligent System for Control of Blood Glucose Level in Critically Ill Patients

摘要

Blood glucose level in the human body is regulated by the pancreas through the production of a harmone namely insulin through a negative feedback system. When it is unable to produce insulin to the patient, the correlation between insulin secretion and blood glucose concentration in the body is impaired. This state of the body is referred as diabetes mellitus. For patients with critical illness of diabetes mellitus continuous treatment is provided in intensive care units. In this work, an intelligent system is developed to control the plasma glucose level in critically ill patients with diabetes mellitus type I. This closed-loop control system monitors and administers appropriate amounts of insulin calculated by control algorithm. The control algorithm is based on sliding scale technique in fuzzy logic framework designed with appropriate rules to deliver accurate insulin dosage. The patient model is simulated using MATLAB and the response shows that the dosages are accurate compared with conventional methods.