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Contribution of different handwriting modalities to differential diagnosis of Parkinson's Disease

机译:不同笔迹型号对帕金森病的鉴别诊断的贡献

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In this paper, we evaluate the contribution of different handwriting modalities to the diagnosis of Parkinson's disease. We analyse on-surface movement, in-air movement and pressure exerted on the tablet surface. Especially in-air movement and pressure-based features have been rarely taken into account in previous studies. We show that pressure and in-air movement also possess information that is relevant for the diagnosis of Parkinson's Disease (PD) from handwriting. In addition to the conventional kinematic and spatio-temporal features, we present a group of the novel features based on entropy and empirical mode decomposition of the handwriting signal. The presented results indicate that handwriting can be used as biomarker for PD providing classification performance around 89% area under the ROC curve (AUC) for PD classification.
机译:在本文中,我们评估了不同手写方式对帕金森病的诊断的贡献。我们分析面向表面运动,空气运动和压力施加在片剂表面上。特别是在先前的研究中很少考虑到空中运动和基于压力的特征。我们表明压力和空中运动也具有与手写诊断帕金森病(PD)相关的信息。除了传统的运动和时空特征之外,我们还基于手写信号的熵和经验模式分解提供了一组新颖的特征。所提出的结果表明,手写可以用作PD的PD的生物标志物,其在ROC曲线(AUC)下的89%面积为PD分类。

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