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Feasibility of thermal strain imaging in noninvasive monitoring of HIFU-mediated local drug delivery

机译:HIFU介导的局部药物递送的非侵袭监测中热应变成像的可行性

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Thermal strain imaging (TSI) is promising for lesion targeting and dose control in thermal-based treatment. We previously developed HIFU and temperature sensitive cerasomes (HTSCs) for local chemotherapy of cancer (Liang et al, Acs Nano 2015). However, the temperature within tissues cannot be noninvasively measured in vivo. The aim of this study was to investigate the feasibility of TSI in noninvasive monitoring of HIFU-medicated doxorubicin (DOX) loaded HTSCs delivery.
机译:热应变成像(TSI)是对基于热基治疗中的病变靶向和剂量控制的承诺。我们以前开发了HIFU和温度敏感的CERAOMES(HTSCS),用于癌症的局部化疗(Liang等,ACS Nano 2015)。然而,组织内的温度不能在体内进行非侵入性测量。本研究的目的是探讨TSI在HIFU - 药物多柔比星(DOX)的非侵入性监测中的可行性加载HTSCS递送。

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