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A pulse-width-adaptive active charge balancing circuit with pulse-insertion based residual charge compensation and quantization for electrical stimulation applications

机译:一种脉冲宽度自适应有源电荷平衡电路,具有基于脉冲插入的残余电荷补偿和电刺激应用量化

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Charge balancing is an important task for the stimulators used in chronic electrical stimulation applications. In this paper, a pulse-width-adaptive (PWA) active charge balancing (ACB) circuit with pulse-insertion based residual charge compensation and quantization is proposed to fulfil this task. The proposed circuit dynamically adapts the pulse width (Tc) of counter phase (Φc) over a stimulation pulses train to achieve charge balancing. The adaptation step ΔTc is based on the quantized residual charge (Qres) of the initial stimulation pulse. Pulse insertion technique is used to quantize Qress and perform instant charge balancing after each stimulation pulse. The PWA ACB circuit mainly consists of an auxiliary pulse generator, residual voltage (Vres) monitoring and Qres quantization block, and a digital controller. A successive approximation (SA) algorithm is implemented in the digital controller for fast Tc searching. The proposed circuit is implemented in 0.18μm CMOS process with 24V LDMOS option, occupying a core area of 700μm by 150μm. The functionality and effectiveness of the circuit are verified through bench-top and animal experiments.
机译:电荷平衡是慢性电刺激应用中使用的刺激器的重要任务。在本文中,提出了一种具有脉冲插入的残余电荷补偿和量化的脉冲宽度自适应(PWA)有源电荷平衡(ACB)电路以满足该任务。所提出的电路在刺激脉冲系上动态地使计数相(φC)的脉冲宽度(TC)用于实现电荷平衡。适配步骤ΔTC基于初始刺激脉冲的量化残余电荷(QRES)。脉冲插入技术用于量化Qress并在每个刺激脉冲后执行即时电荷平衡。 PWA ACB电路主要由辅助脉冲发生器,剩余电压(VRE)监测和QRES量化块以及数字控制器组成。连续近似(SA)算法在数字控制器中实现了快速TC搜索。所提出的电路以0.18μm的CMOS工艺实现,具有24V LDMOS选项,占核心区域为700μm的150μm。电路的功能和有效性通过台式和动物实验验证。

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