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NUMERICAL SIMULATION OF CELL MOTILITY AT LOW REYNOLDS NUMBER

机译:低雷诺数下细胞运动的数值模拟

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In the present work, we have introduced a new method for modeling low Reynolds number motility based on the finite volume method. The code we have developed is implemented in a commercially available software (Ansys FLUENT v12.1), making it accessible and adaptable. We have validated the code in two ways: first, we compare with the analytical solution of flow around a point force (the Stokeslet); second, we compare with swimming speeds from experimental observations. Unlike previous methods which must be solved with a far-field boundary condition, our code is implemented with no-slip wall boundary conditions. In the future, we hope to expand our model further with the built-in capabilities of FLUENT, namely: parallelization, which presents the opportunity for researchers to scale-up the number of micro-swimmers studied; heat and mass transfer models within the domain to simulate chemotaxis; and the ability to implement a non-Newtonian fluid.
机译:在目前的工作中,我们介绍了一种基于有限体积法建模低雷诺数运动性的新方法。我们开发的代码在市售软件(Ansys FLUENT v12.1)中实现,使其可访问和适应。我们以两种方式对代码进行了验证:首先,我们与围绕点力(斯托克斯let)的流动的解析解进行比较。其次,我们将实验观察结果与游泳速度进行比较。与以前的方法必须使用远场边界条件解决的方法不同,我们的代码是在不滑墙边界条件下实现的。将来,我们希望借助FLUENT的内置功能进一步扩展我们的模型,即:并行化,这为研究人员提供了扩大所研究的微型游泳机数量的机会;域内的传热和传质模型以模拟趋化性;以及实现非牛顿流体的能力。

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