Modeling and Simulation of Temperature Distribution in Laser-tissue Interaction

摘要

In this paper, modeling and simulation of interaction between light sources and living biological tissue is studied. One of the most important results of physical interactions of light with biological tissue is thermal changes which is a consequence of absorption of light. The severity of the effects are dependent upon several factors, including exposure duration, wavelength of the beam, energy of the beam, the area and type of tissue exposed to the beam. The temperature response of tissue irradiation is governed by extensively used Pennes bio-heat equation in a 3-dimensional space. The Pennes equation is solved for a single layer model of the human skin to predict the temperature distribution using different laser light source radiation burns at as steady state. The numerical solutions are obtained by the Finite Element Method (FEM), in which the geometry studied is divided into a finite element mesh. This method gives better description of the geometry with smaller number of nodes. Less memory space and disk space with shorter run times make this method more advantageous to other numerical solution techniques. Temperature contours and penetration depths are plotted in three dimensional spaces. These results are compared with finite volume approach which exists in literature. In this work, it is demonstrated that by adjusting exposure duration, wavelength of the beam, energy of the beam, and the area and type of tissue, temperature effects on tissue can be altered.