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Simulating Parkinson's disease patient deficits using a COVIS-based computational model

机译:使用基于COVIS的计算模型模拟帕金森氏病患者虚弱

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摘要

COVIS is a neurobiologically motivated model of perceptual category learning. It includes two competing systems: the hypothesis-testing system mediates learning and performance in tasks requiring explicit reasoning; the procedural system mediates learning and performance in tasks that are achieved procedurally through trial and error learning when no explicit rule/strategy exists. Here we describe a computational implementation of COVIS used to model the differential effects of dopamine depletion on performance in a perceptual category-learning task and the simplified Wisconsin Card Sorting Test (WCST).
机译:COVIS是感知类别学习的神经生物学动机模型。它包括两个相互竞争的系统:假设检验系统介导需要明确推理的任务中的学习和表现;当没有明确的规则/策略存在时,程序系统会通过尝试性学习和错误学习来介导在通过程序实现的任务中的学习和绩效。在这里,我们描述了一种COVIS的计算实现方式,该算法用于在感知类别学习任务和简化的威斯康星卡片分类测试(WCST)中对多巴胺消耗对性能的差异影响进行建模。

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