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A multi-Biclustering Combinatorial Based algorithm

机译:一种基于多聚类组合的算法

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In the last years a large amount of information about genomes was discovered, increasing the complexity of analysis. Therefore the most advanced techniques and algorithms are required. In many cases researchers use unsupervised clustering. But the inability of clustering to solve a number of tasks requires new algorithms. So, recently, scientists turned their attention to the biclustering techniques. In this paper we propose a novel biclustering technique, that we call Combinatorial Biclustering Algorithm (BCA). This technique permits to solve the following problems: 1) classification of data with respect to rows and columns together; 2) discovering of the overlapped biclusters; 3) definition of the minimal number of rows and columns in biclusters; 4) finding all biclusters together. We apply our model to two synthetic and one real biological data sets and show the results.
机译:在最近几年中,发现了大量有关基因组的信息,从而增加了分析的复杂性。因此,需要最先进的技术和算法。在许多情况下,研究人员使用无监督聚类。但是集群无法解决许多任务需要新的算法。因此,最近,科学家将注意力转向了双聚类技术。在本文中,我们提出了一种新颖的双聚类技术,称为组合双聚类算法(BCA)。这种技术可以解决以下问题:1)关于行和列一起的数据分类; 2)发现重叠的双簇; 3)定义二元组中行和列的最小数量; 4)一起找到所有的biclusters。我们将模型应用于两个合成的和一个真实的生物学数据集并显示结果。

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