Quantitative evaluation of hand movement in spiral drawing for patients with Parkinson's disease based on modeling in polar coordinate system with varied origin

摘要

Parkinson's disease is one of the most common neurodegenerative disorders, and its complex symptoms bring some difficulties for the clinical diagnosis. In this study, a method based on mathematical modeling of hand movement in spiral drawing was proposed to quantitatively evaluate the performance of patients with Parkinson's disease. Unlike the previous works, the hand movement data in spiral drawing were analyzed and modeled under the polar coordinate system with varied origin. Experimental results gained from the model showed that this method of evaluation was consistent with the clinical diagnosis before and after deep brain stimulation operation. The proposed method based on mathematical modeling in polar coordinate system with varied origin is effective in clinical diagnosis, and it provides a basis for quantitative evaluating the effectiveness of surgery and treatment.