PARKINSON'S DISEASE MODEL MOUSE, METHOD FOR PRODUCING THE SAME, AND SCREENING METHOD AND EVALUATION METHOD FOR THERAPEUTIC AGENT FOR PARKINSON'S DISEASE EACH USING THE MOUSE

摘要

PPROBLEM TO BE SOLVED: To provide a Parkinson's disease model mouse which can develop the symptoms of Parkinson's disease reliably in the early stage, a process for producing the mouse and a screening method and an evaluation method for a therapeutic agent for Parkinson's disease, each of which utilizes the mouse. PSOLUTION: The Parkinson's disease model mouse is characterized in that a gene encoding parkin is inactivated and IRP2 is expressed specifically in nerve cells. PCOPYRIGHT: (C)2011,JPO&INPIT