Commercial Suborbital Reusable Launch Vehicles (sRLVs) are in development for transporting people and/or research payloads "quickly, frequently, and safely" to the edge of space. Their business cases are typically based on 30-to-45-minute flights with rapid re-flight capabilities due to high levels of vehicle reusability designed to signiflcantly drive down costs per flight. We focus here on several research payload configuration and use aspects important for the facilitation of rapid sRLV flight rates. Major benefits are anticipated for what we call "reusable" payloads and related processes to support these frequent flights. Several payload reusability and rapid processing concepts are reviewed and some examples given. Projected benefits for researchers are profiled as well as the NASA Flight Opportunities (FO) Program that will competitively solicit, select and fund flights of research payloads on emerging sRLVs and routinely utilized parabolic aircraft. A description of the FO Program's collaboration, pathfinder and researcher "engagement" roles is provided that is deemed essential for developing a "payloads pipeline" for these flights driven by customer demand.
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