MICRO-VISUALIZING ASSAY OF DRUG DELIVERY SYSTEM USING 2-COLOR OPTICAL COHERENCE DOSIGRAPHY

摘要

2-Color Optical Coherence Dosigraphy, which could visualize micro-scale drug infiltration, was applied to lipidrich plaques of rabbit with drug administration. Calculated distributions of absorption coefficient had good coincidence with drug infiltration into tissue. Therefore, 2C-OCD has a promising modality for micro-visualizing assay of drug delivery system.