Experimental Research on the Cytotoxicity of CdSe Nanocrystals with the Irradiation of Violet Light

摘要

The present study processed the absorption spectrum of CdSe nanocrystals (Ncs) which was modified by mercaptoacetic acid (MA). Based on this, the LEDs whose emission peak is near the absorption peak of the NCs were selected to form a LED array. The leukemia cell line HL60 was cultured in two 96-well plates and incubated with different concentrations of MA-Coated CdSe NCs. One of the 96-well microplates was irradiated by the LED array mentioned above, and the other wasn't. Then the viability of the cells on both microplates was determined using CCK-8 assay. The results in vitro demonstrated that the ability of MA-Coated CdSe NCs to induce cell death can be promoted under the irradiation of the light source we used.