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Implantable stimulator for bipolar stimulation without charge balancing circuits

机译:无电荷平衡电路的可植入刺激器,用于双极刺激

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It is critically important to maintain charge balance in neural stimulation, employing biphasic current pulses. Any mismatch in biphasic current pulses will result in charge imbalance, possibly leading to tissue damage. In this paper, we propose an implantable stimulator for bipolar stimulation to minimize the mismatch of biphasic current pulses, without dc blocking capacitors or charge balancing circuits. Using 0.35μm HV CMOS process with 20V power supply, the maximum mismatch between cathodic and anodic current is achieved less than 0.4μA out of full scale current of 1mA. (equivalent to 11 bit accuracy at 1mA) Residual dc current of less than 1nA is achieved with shorting enabled, under 0.1ms stimulation for each cathodic and anodic phase out of 3ms period.
机译:使用双相电流脉冲在神经刺激中保持电荷平衡至关重要。双相电流脉冲的任何不匹配都会导致电荷失衡,可能导致组织损伤。在本文中,我们提出了一种用于双极刺激的植入式刺激器,以最大程度地减小两相电流脉冲的失配,而无需隔直电容器或电荷平衡电路。使用0.35μmHV CMOS工艺和20V电源,在1mA的满量程电流中,阴极和阳极电流之间的最大失配小于0.4μA。 (相当于1mA时的11位精度)启用短路后,在3ms周期内的每个阴极和阳极相位都受到0.1ms激励的情况下,可获得小于1nA的残余直流电流。

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