MODULATION OF INTESTINAL UPTAKE OF COPOLYMERIC MICELLES NANOPARTICLES BY OPTIMIZING THEIR SURFACE HYDROPHOBICITY AND MUCOADHESIVENESS

机译：通过优化其表面疏水性和粘膜粘性来调节肠溶性共聚胶束纳米颗粒的摄取

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The composition of the copolymeric materials forming the micellar carriers has been optimized so that all the characteristics such as particle size, surface hydrophobicity, appropriate pH sensitiveness and mucoadhesivity are mani-fested to their maximum extent so far as their translocation from gut to blood is concerned.

机译：已经优化了形成胶束载体的共聚材料的组成，从而可以最大程度地控制所有特性，例如粒径，表面疏水性，适当的pH敏感性和粘膜粘附性，只要它们从肠道向血液易位即可。

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《International symposium on controlled release of bioactive materials;Consumer diversified products conference》|2001年|p.656-657|共2页
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M. Sahni; S. Mitra; A.N. Maitra;
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中图分类基础医学;
关键词
oral drug delivery; bioadhesion; biodegradeable polymer; gastrointestinal transit; pH-controlled release;

机译：口服药物递送;生物粘附可生物降解的聚合物胃肠道转运pH控制释放;

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MODULATION OF INTESTINAL UPTAKE OF COPOLYMERIC MICELLES NANOPARTICLES BY OPTIMIZING THEIR SURFACE HYDROPHOBICITY AND MUCOADHESIVENESS

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