DESIGN AND EVALUATION OF A NEW TRANSDERMAL FORMULATION CONTAINING ESTRADIOL

摘要

A new formulation for estradiol topical administration was developed, consisting in an anhydrous gel which suddenly gives an invisible film. In particular, the formula which contain Polymer-Len and Klucel HF can be a good candidate for a new formulation given its good technological characteristic, its patient compliance enhancement and its permeation behaviour.