A novel microdialysis glucose sensor system based on co-immobilizing on Au micro-electrode by sol-gel technique

摘要

A microdialysis sensor system for continuous glucose measurements has been developed. The sensor is based on co-immobilizing glucose oxidase (GOD) with the catalase by a sol-gel technique on the surface of silicon bases with two pattern of Au microelectrodes. A graduated ("sandwich") immobilizing method is performed to improve the stability and the lifetime of the co-enzyme system. The response of the system was in good order. Above all, we developed a new geometry of the bispiral microelectrode with numerical analysis of its electrochemical character.