Synthesis and properties of unprecedented thermosensitive cyclotriphosphazene derivatives

摘要

During the past decade, there has been an explosive growth in studies of thermosensitive polymers, a new class of stimuli-sensitive materials, that have a great potential as drug delivery systems (DDS), membranes, bioseparation, purification, sensors, switch, and recording materials.~1-2 Especially, the polymers with lower critical solution temperature (LCST) near or below the body temperature are of great interest for the biomedical applications such as local drug delivery and body temperature sensitive drug release.~3