Activity of amphotericin b associated to polymeric carriers against extracellular and intracellular candida albicans

摘要

Ethylene oxide and propylene oxide block copolymers (poloxamers) are widely used in pharmaceutical preparations as agents for drug solubilization and also as stabilizer agents in drug delivery systems. So far, a lot of biological properties have been attribuited to them, many of which are possibly mediated by their interaction with cell plasma membranes~1.