Application of the new methodology of quantitative evaluation ofmorphofunctional changes in RBCs induced by low-dose irradiation of donors,

摘要

Abstract: We are reporting on the results obtained in the development of our previous paper. We have implemented the previously described unified approach of particle image velocimetry and computer morphodensitometry trying to find correlation between morphofunctional and dynamic parameters of red blood cells of human donors who had undergone low-doze ionizing irradiation conventionally used in radiology. Specifically we examined the suspension of RBCs obtained from children who had accidentally or therapeutically undergone irradiation with different doses (0.03 - 0.04 Gy), and compared them to controls. Our experiments have shown the existence of correlation between the rheological and morphometric indexes obtained with the help of the computer image processing system Diamorph.!5