Keratin Nanomaterial Coating Limits Epithelial Downgrowth Around Percutaneous Devices

摘要

The present study highlights the importance of biochemical cues (i.e., Keratin coatings) and mechanical stability (i.e., porous coating that allows tissue ingrowth) for preventing downgrowth around percutaneous devices. The iKTN and gKOS coatings could benefit these devices, provided in vivo degradation properties of these protein coatings are further optimized. This finding highlighted the importance of testing the efficacy of devices at longer follow-up times than what has been previously reported in the literature.