Preliminary fusion of EEG and MRI with phenotypic scores in children with epilepsy based on the Canonical Polyadic Decomposition

摘要

Cognitive and behavioural impairments in early-onset epilepsy affect the children and families’ quality of life. Our ability to detect these impairments is limited, and it requires laborious questionnaires. Here, we describe a pilot study exploring the fusion of resting-state EEG, volumetric MRI, and phenotypic scores of child development based on the Canonical Polyadic Decomposition, expanding the recently presented Joint EEG-Development Inference (JEDI) model. Pilot data fusion was performed on functional, structural and developmental brain features of 29 preschool children diagnosed with epilepsy. The results suggest that combining multimodal brain data towards a comprehensive analysis of brain development in young children is plausible.