INTEGRATED MANUFACTURING WITH MICROBIAL HOSTS FOR FAST PROCESS DEVELOPMENT AND PRODUCTION

摘要

Integrated and continuously operating processes for recombinant protein drugs that rely on non-mammalian hosts offer potential advantages compared to CHO-based platforms for the rapid production of high-quality biopharmaceuticals. This talk will describe insights and technical advances related to the realization of microbial-based production of proteins gained over the past four years in developing a small prototype system for on-demand production of biologies (Figure).