In Vitro Wear and Wear Particle Analysis of Conventional Polyethylene Tibial Inserts for Revision Condylar Constrained Knee Systems

摘要

The wear rates generated by Group A and Group B are similar and below the osteolytic limit of 80 mm3 per year which is equivalent to 74 mg/Mc. While this threshold was developed for hip penetration rates, it represents a helpful benchmark in the absence knee-specific data'. The wear rates are also lower compared to many primary knee systems reported2. Numerous wear debris/particles parameters such size, shape, volume, concentration and composition are reported to influence the biological response causing osteolysis. In general, the sizes of PE particles range from nanometer to millimeter although majority of particles are found to be in submicron range. Also, the wear PE particles resulting from knee testing are higher sizes as compared to those from hip testing. The sizes and the morphology of PE particles resulting from this testing were in a similar range to those reported in the literature studies.