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Sleep apnea detection using blood pressure signal

机译:使用血压信号检测睡眠呼吸暂停

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Sleep apnea is a common respiratory disease. Apnea affects sleep quality, reduces people's life standards, and it can result in death at advanced stage. Therefore the ability to detect the apnea quickly and accurately is important for the treatment of this disease. Apnea is diagnosed by specialists however this is a long and exhausting process. Accordingly, a decision support system that automatically diagnoses apnea has been developed to facilitate this process and make it more objective. The developed decision support system in this study is based on patient's blood pressure signals instead of traditional Polysomnography (PSG) records, which requires various physiological signals measured from the patients. In the examined blood pressure signals, the change that results from each heart beat was determined and heart rate variability (HRV) was calculated based on these changes. At the same time, maximum and minimum amplitude values were found for each change period and amplitude variability vector was created. The features for each epoch were determined using the generated amplitude variability vector and HRV data. Presence of apnea in each epoch is classified with determined features and with the use of “Quadratic SVM” classifier. The Quadratic SVM classifier was trained with 87.5% accuracy and then the system is tested. As a result 75.4% sensitivity and 75% positive predictive values were obtained.
机译:睡眠呼吸暂停是一种常见的呼吸系统疾病。呼吸暂停会影响睡眠质量,降低人们的生活水平,并可能导致晚期死亡。因此,快速准确地检测出呼吸暂停的能力对于治疗该疾病很重要。呼吸暂停由专家诊断,但这是一个漫长而费力的过程。因此,已经开发了自动诊断呼吸暂停的决策支持系统以促进该过程并使之更加客观。本研究中开发的决策支持系统基于患者的血压信号,而不是传统的多导睡眠图(PSG)记录,后者需要从患者身上测量各种生理信号。在检查的血压信号中,确定每次心跳导致的变化,并根据这些变化计算心率变异性(HRV)。同时,找到每个变化周期的最大和最小振幅值,并创建振幅可变性矢量。使用生成的振幅可变性矢量和HRV数据确定每个时期的特征。每个时期的呼吸暂停的存在都通过确定的特征进行分类,并使用“ Quadratic SVM”分类器进行分类。对二次SVM分类器进行了87.5%的准确度训练,然后对系统进行了测试。结果,获得了75.4%的灵敏度和75%的阳性预测值。

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