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Propensity Score Stratification Using Support Vector Machine in HIV AIDS Case

机译:基于支持向量机的艾滋病病例倾向得分分层

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Many observational studies applied in the field of health, but Randomized Controlled Trials (RCT) is not always can be applied because it is directly related to human life. Therefore, a method is needed to solve the problem of bias as the effect of non-random observation and unbalanced covariates using propensity score (PS), it is Propensity Score Stratification (PSS). The purpose of PSS is to obtain a strata group that balance on each covariate. The PSS estimation of this research is using support vector machine (SVM). The case used in this research is opportunistic infection of HIV AIDS at Grati Health Center in Pasuruan district with the number of respondents are 150 patients. In the case of opportunistic infections HIV AIDS found that giving ARV therapy becomes confounding variable.The highest accuracy of PSS SVM on strata is 4, that is 64%. Estimation of treatment effects (ATE) gave results that the variable of ARV therapy is a variable that influence the opportunistic infections (Y) in HIV AIDS patients. The number of strata that reduce the largest bias is in the strata of 4 with the percent bias reduction (PBR) is 37.168% with the smallest standard error value is 0.075 and ATE value is 0.516.
机译:在健康领域应用了许多观察性研究,但由于与人类生活直接相关,因此并非总是可以应用随机对照试验(RCT)。因此,需要一种使用倾向性得分(PS)来解决非随机观察和不平衡协变量影响的偏差问题的方法,即倾向性得分分层(PSS)。 PSS的目的是获得在每个协变量上保持平衡的阶层组。这项研究的PSS估计使用支持向量机(SVM)。本研究中使用的病例是帕苏鲁安区Grati卫生中心的机会性艾滋病毒感染,被调查者为150名患者。在机会感染的情况下,HIV / AIDS发现进行抗逆转录病毒治疗变得令人困惑。分层中PSS SVM的最高准确度是4,即64%。估计治疗效果(ATE)得出的结果是,抗逆转录病毒疗法的变量是影响HIV AIDS患者机会性感染(Y)的变量。减少最大偏差的层数在4层中,偏差减少百分比(PBR)为37.168%,最小标准误差值为0.075,ATE值为0.516。

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