CONCLUSION: This study demonstrates that the newly developed Mg/PCL scaffolds are able to enhance the mechanical property and inferior bioactivity of pure PCL scaffold so as to encourage bone formation and ingrowth. TMSPM silane-coupling treatment can further enhance the mechanical property of the scaffolds. Hence, all these promising results have shown that the modified Mg/PCL hybrid porous scaffolds can be potentially applied in large bone defect fixation.
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